Dr. Brian Karaan
    The Anti-Inflammatory Plate: Building Meals That Heal

    The Anti-Inflammatory Plate: Building Meals That Heal

    3 min readApril 15, 2026
    Dr Brian Karaan

    Dr. Brian Karaan

    Author


    Inflammation Isn't Always Bad

    Acute inflammation is your body's healing response. Cut your finger, and inflammation rushes immune cells to the site. That's the system working perfectly.

    The problem is chronic, low-grade inflammation — a smoldering fire that never fully extinguishes. It's driven by processed food, chronic stress, poor sleep, and sedentary lifestyles. And it's implicated in virtually every chronic disease.

    The Standard American Diet Problem

    The typical Western diet is profoundly pro-inflammatory:

  1. Omega-6 to omega-3 ratio: 20:1 (should be 2-4:1)
  2. Added sugar: 73g/day average (should be under 25g)
  3. Ultra-processed foods: 60% of calories for the average American
  4. Fiber: 15g/day average (should be 30g+)
  5. You don't need a supplement to reduce inflammation. You need to stop pouring gasoline on the fire.

    Building the Anti-Inflammatory Plate

    The Template

    Every meal should aim for this composition:

  6. 50% → Non-starchy vegetables (diverse colors)
  7. 25% → Quality protein (wild fish, pastured eggs, legumes)
  8. 15% → Complex carbohydrates (intact whole grains, roots)
  9. 10% → Healthy fats (olive oil, avocado, nuts, seeds)
    • Herbs and spices liberally

    The Power Players

    Some foods have outsized anti-inflammatory effects:

  10. Fatty fish (salmon, sardines, mackerel) — EPA and DHA directly suppress inflammatory cytokines
  11. Turmeric — curcumin inhibits NF-κB, but needs black pepper (piperine) for absorption
  12. Berries — anthocyanins reduce CRP (C-reactive protein) levels
  13. Extra virgin olive oil — oleocanthal has ibuprofen-like anti-inflammatory properties
  14. Leafy greens — rich in folate, which regulates homocysteine (an inflammatory marker)
  15. Foods to Minimize

    Food Why
    Seed oils (soybean, corn, sunflower) Excessive omega-6, oxidize easily
    Refined sugar Triggers inflammatory cascades
    Processed meats Contain AGEs and nitrosamines
    Refined grains Rapid glucose spikes → inflammatory
    Excess alcohol Damages gut lining, increases LPS translocation

    A Day of Anti-Inflammatory Eating

    Breakfast: Greek yogurt with walnuts, blueberries, ground flaxseed, and a drizzle of raw honey.

    Lunch: Large arugula salad with roasted sweet potato, chickpeas, avocado, sunflower seeds, and lemon-tahini dressing.

    Dinner: Baked wild salmon with roasted broccoli, sautéed garlic spinach, and brown rice. Seasoned with turmeric, black pepper, and fresh dill.

    Snack: Apple slices with almond butter and a sprinkle of cinnamon.

    The 80/20 Approach

    Perfection isn't the goal. Consistency is. If 80% of your meals follow anti-inflammatory principles, you'll see meaningful changes in energy, joint comfort, skin clarity, and lab markers within 6–8 weeks.

    Start with one meal. Get it right consistently. Then expand. That's how lasting change happens.

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    Dr Brian Karaan

    Dr. Brian Karaan

    Dr. Brian Karaan, MD. Mayo Clinic alumni. Functional medicine physician in Denver, CO for 28 years. Spent 22 years developing the gut-based protocol that Harvard confirmed in 2024. Treated 4,000+ patients. Created Sugar Harmony to bring the protocol to everyone who needs it.

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